SCHEMBL24909856

SCHEMBL24909856

N#Cc1cc(Br)c(O)c(-c2ccccc2F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
TTR P02766 2/20 0.55
ALB P02768 2/20 0.55
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
CCNE2 O96020 1/20 0.36
EGFR P00533 1/20 0.36
CDK1 P06493 1/20 0.36
CDK4 P11802 1/20 0.36
SRC P12931 1/20 0.36
CCND1 P24385 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK2 P24941 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909849 0.85 TTR (0.60) MEN1KMT2ATTRALBGABRA1
SCHEMBL24909760 0.81 TTR (0.55) MEN1KMT2ATTRALBGABRA1
SCHEMBL3644912 0.81 GABRG2 (0.40) MEN1KMT2ATTRALBGABRG2
SCHEMBL24909889 0.81 KMT2A (0.55) MEN1KMT2ATTRALBGABRA1
SCHEMBL24909851 0.80 KMT2A (0.49) MEN1KMT2ATTRALBGABRA1
SCHEMBL24909845 0.80 TTR (0.49) MEN1KMT2ATTRALBGABRA1
SCHEMBL24909344 0.80 MEN1 (0.49) MEN1KMT2ATTRALBGABRA1
SCHEMBL24909360 0.79 MEN1 (0.60) MEN1KMT2ATTRALBEGFR
SCHEMBL23621220 0.77 MEN1 (0.53) MEN1KMT2ATTRALBGABRG2
SCHEMBL24909772 0.77 TTR (0.53) MEN1KMT2ATTRALBGABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 MEN1 3221/4885KMT2A 847/4885TTR 4497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.