SCHEMBL2490986

SCHEMBL2490986

Cc1cc2nc(C)c(C)nc2cc1C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 3/20 0.57
KDM4E B2RXH2 5/20 0.55
MAPT P10636 4/20 0.55
NPC1 O15118 5/20 0.52
RAB9A P51151 4/20 0.52
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 4/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 1/20 0.46
GAA P10253 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
FABP6 P51161 1/20 0.41
BACE1 P56817 1/20 0.40
PDGFRB P09619 1/20 0.40
KDR P35968 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13388975 0.86 NQO2 (0.72) NQO2KDM4EMAPTNPC1RAB9A
SCHEMBL13388977 0.86 TDP1 (0.46) NQO2KDM4EMAPTNPC1RAB9A
SCHEMBL12355738 0.85 NQO2 (0.50) NQO2KDM4EMAPTNPC1RAB9A
SCHEMBL2662790 0.81 ALDH1A1 (0.50) NQO2KDM4EMAPTNPC1RAB9A
SCHEMBL10784379 0.81 KDM4E (0.50) NQO2KDM4EMAPTNPC1RAB9A
SCHEMBL11204584 0.81 TERT (0.60) NQO2KDM4EMAPTNPC1RAB9A
SCHEMBL2490947 0.81 KDM4E (0.56) NQO2KDM4EMAPTNPC1RAB9A
SCHEMBL9695318 0.81 NQO2 (0.46) NQO2KDM4EMAPTNPC1RAB9A
SCHEMBL2246917 0.80 NQO2 (0.57) NQO2KDM4EMAPTNPC1RAB9A
SCHEMBL31429032 0.80 TDP1 (0.43) NQO2KDM4EMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-8330039-B2 Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-11 US disclosed
CN-102292826-A Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound 2011-12-21 CN disclosed
EP-2380208-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. du Pont de Nemours and Company (US) 2011-10-26 EP disclosed
WO-2010085664-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 WO disclosed
US-20100180947-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-22 US disclosed
US-7704751-B2 Polymeric fluorescent chemical sensor 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-04-27 US disclosed
US-20080070320-A1 FLUORESCENT CHEMICAL SENSOR 3M INNOVATIVE PROPERTIES COMPANY 2008-03-20 US disclosed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
US-4323682-A BLEACHING CATALYSTS CIBA GEIGY AG (CH) 1982-04-06 US disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed
US-4202698-A DYE BLEACH CATALYSTS CIBA-GEIGY AG (CH) 1980-05-13 US disclosed