SCHEMBL24910073

SCHEMBL24910073

N#Cc1cc(-c2ccc(OC(F)(F)F)cc2)c(O)c(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 4/20 0.41
SCN5A Q14524 2/20 0.41
TRPA1 O75762 1/20 0.41
XDH P47989 1/20 0.40
SLC22A12 Q96S37 1/20 0.40
FNTB P49356 3/20 0.40
SIGMAR1 Q99720 1/20 0.40
HRH1 P35367 1/20 0.40
KDM1A O60341 1/20 0.40
MAOB P27338 1/20 0.40
FNTA P49354 2/20 0.39
ACLY P53396 1/20 0.39
PGGT1B P53609 1/20 0.39
KIF11 P52732 1/20 0.38
AR P10275 3/20 0.38
PGR P06401 2/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909759 0.86 ADORA1 (0.46) XDHSLC22A12FNTBFNTAPGGT1B
SCHEMBL24909916 0.84 MEN1 (0.47) SCN9ASCN5ATRPA1FNTBSIGMAR1
SCHEMBL24909729 0.82 KDM4E (0.43) TRPA1XDHSLC22A12KIF11AR
SCHEMBL5099610 0.82 KDM1A (0.50) SCN9ASCN5ATRPA1FNTBSIGMAR1
SCHEMBL24909930 0.80 KIF11 (0.39) SCN9AXDHSLC22A12KDM1AKIF11
SCHEMBL24909891 0.78 AR (0.43) XDHSLC22A12ARPGRAKR1C2
SCHEMBL24909915 0.77 KIF11 (0.41) XDHSLC22A12KIF11ARPGR
SCHEMBL24909991 0.76 KIF11 (0.47) XDHSLC22A12KIF11
SCHEMBL24910055 0.76 PDK2 (0.44) XDHSLC22A12KIF11ARPGR
SCHEMBL24909774 0.76 KIF11 (0.40) XDHSLC22A12KIF11ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 SCN9A 2151/4885SCN5A 1375/4885TRPA1 882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.