Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491027 | 0.85 | KDM4E (0.53) | LMNAALDH1A1MAPK1POLBKDM4E | |
| Ammonia Solution, Strong SCHEMBL28585108 | 0.83 | KDM4E (0.52) | LMNAALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL7074713 | 0.83 | PDE10A (0.56) | LMNAPDE10AALDH1A1MAPK1POLB | |
| Hydrochloric Acid SCHEMBL28608867 | 0.81 | KDM4E (0.50) | LMNAALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL22342229 | 0.81 | ALDH1A1 (0.55) | LMNAPDE10AALDH1A1MAPK1POLB | |
| SCHEMBL16424551 | 0.80 | LMNA (0.51) | LMNAPDE10AALDH1A1MAPK1POLB | |
| SCHEMBL14473916 | 0.80 | LMNA (0.51) | LMNAPDE10AALDH1A1MAPK1POLB | |
| SCHEMBL4355754 | 0.80 | LMNA (0.56) | LMNAPDE10AALDH1A1MAPK1POLB | |
| SCHEMBL4344595 | 0.80 | LMNA (0.51) | LMNAPDE10AALDH1A1MAPK1POLB | |
| SCHEMBL11328179 | 0.79 | PDE10A (0.53) | LMNAPDE10AALDH1A1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228151-A | QUINOXALINE DIOXIDE | L'OREAL (FR) | 1980-10-14 | — | — | US | claimed |
| CN-117945995-A | Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof | 中国科学院青海盐湖研究所 | 2024-04-30 | — | — | CN | disclosed |
| WO-2021116872-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CABOTEGRAVIR | VIIV HEALTHCARE COMPANY (US) | 2021-06-17 | — | — | WO | disclosed |
| WO-2017205078-A1 | METHODS FOR TREATING HEPATITIS B VIRUS INFECTIONS USING NS5A, NS5B OR NS3 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2017-11-30 | — | — | WO | disclosed |
| WO-2017184670-A2 | METHODS FOR TREATING ZIKA VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2017-10-26 | — | — | WO | disclosed |
| US-9770452-B2 | Quinoxaline derivatives as GPR6 modulators | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-09-26 | — | — | US | disclosed |
| EP-2978759-B1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | GILEAD SCIENCES INC (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170035775-A1 | QUINOXALINE DERIVATIVES AS GPR6 MODULATORS | ENVOY THERAPEUTICS, INC. | 2017-02-09 | — | — | US | disclosed |
| WO-2015095430-A1 | METHODS AND INTERMEDIATES FOR THE PREPARATION OF MACROLACTAMS | MERCK SHARP & DOHME CORP. (US) | 2015-06-25 | — | — | WO | disclosed |
| CN-102143951-A | Tri-substituted pyrimidine compounds and their use as PDE10 inhibitors | MITSUBISHI TANABE PHARMA CORP | 2011-08-03 | — | — | CN | disclosed |
| US-4138410-A | Flavoring agent | FIRMENICH & CIE (CH) | 1979-02-06 | — | — | US | disclosed |
| US-4126618-A | FLAVOR ADDITIVES FOR FOODS AND BEVERAGES | FIRMENICH & CIE (CH) | 1978-11-21 | — | — | US | disclosed |
| US-4085109-A | Pyridine sulfur flavoring agents | FIRMENICH & CIE (CH) | 1978-04-18 | — | — | US | disclosed |
| US-3989713-A | Pyrrylmethylthio flavoring agents | FIRMENICH & CIE (CH) | 1976-11-02 | — | — | US | disclosed |
| US-3952026-A | FLAVOR ADDITIVE FOR FOODS AND BEVERAGES | FIRMENICH & CIE (CH) | 1976-04-20 | — | — | US | disclosed |
| US-3952024-A | FLAVOR ADDITIVE FOR FOODS AND BEVERAGES | FIRMENICH & CIE (CH) | 1976-04-20 | — | — | US | disclosed |
| US-3943260-A | TETRAHYDRO-THIO-PHEN-3-ONES | FIRMENICH & CIE (CH) | 1976-03-09 | — | — | US | disclosed |
| US-3931245-A | FURYLALKYLTHIOL CARBOXYLATES | FIRMENICH & CIE (CH) | 1976-01-06 | — | — | US | disclosed |
| US-3931166-A | FLAVORANTS | FIRMENICH & CIE (CH) | 1976-01-06 | — | — | US | disclosed |
| US-3931246-A | FURYLALKYL-THIOETHERS | FIRMENICH & CIE (CH) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170035775-A1 | QUINOXALINE DERIVATIVES AS GPR6 MODULATORS | GPR6, GRM6, GPR65 | LMNA 4739/4885PDE10A 793/4885ALDH1A1 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.