Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25944376 | 0.83 | — | — | |
| SCHEMBL26170674 | 0.77 | SLC7A5 (0.30) | — | |
| SCHEMBL16158891 | 0.73 | — | — | |
| SCHEMBL16158896 | 0.73 | — | — | |
| SCHEMBL13073514 | 0.73 | — | — | |
| SCHEMBL21739321 | 0.71 | L3MBTL1 (0.30) | — | |
| SCHEMBL12477813 | 0.70 | S1PR1 (0.42) | CARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL23366034 | 0.70 | PKM (0.31) | — | |
| SCHEMBL12749918 | 0.70 | PKM (0.31) | — | |
| SCHEMBL26815281 | 0.70 | PKM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601297-B9 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC (US) | 2023-05-24 | — | — | EP | disclosed |