SCHEMBL24911522

SCHEMBL24911522

Clc1ccc2c(c1)oc1cc3ncccc3cc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 3/20 0.56
AHR P35869 5/20 0.51
CASP6 P55212 1/20 0.44
PDGFRB P09619 1/20 0.41
PDGFRA P16234 1/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 1/20 0.39
PIK3CG P48736 1/20 0.38
SOS2 Q07890 1/20 0.38
NCOA1 Q15788 1/20 0.38
HTT P42858 3/20 0.38
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24910918 0.94 NR4A2 (0.56) NR4A2AHRCASP6PDGFRBPDGFRA
SCHEMBL24911457 0.85 NR4A2 (0.56) NR4A2AHRCASP6PDGFRBPDGFRA
SCHEMBL26423196 0.83 MAPT (0.49) AHRCASP6PDGFRBPDGFRANPC1
SCHEMBL23944309 0.79 NR4A2 (0.42) NR4A2AHRCASP6PDGFRBPDGFRA
SCHEMBL26423259 0.79 PDGFRB (0.41) NR4A2CASP6PDGFRBPDGFRANPC1
SCHEMBL24155359 0.79 AHR (0.69) AHRALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL23944918 0.78 CASP6 (0.46) NR4A2AHRCASP6PDGFRBPDGFRA
SCHEMBL24958163 0.77 AHR (0.53) NR4A2AHRNPC1RAB9AALDH1A1
SCHEMBL26423212 0.76 MAPT (0.49) AHRCASP6PDGFRBPDGFRANPC1
SCHEMBL26423246 0.76 ALDH1A1 (0.46) NR4A2CASP6PDGFRBPDGFRANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023287255-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-01-19 WO disclosed