SCHEMBL2491202

SCHEMBL2491202

CCC(=O)COCC1C(C)CCC1C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14346425 0.93 TDP1 (0.31) TDP1
SCHEMBL2516396 0.85 ALDH1A1 (0.30)
SCHEMBL2516545 0.81 NAAA (0.38)
SCHEMBL17336915 0.80 SMN1; SMN2 (0.33) TDP1
SCHEMBL14975548 0.80
SCHEMBL2467324 0.80 NAAA (0.41) TDP1
SCHEMBL17336931 0.79 ALDH1A1 (0.30)
SCHEMBL14975180 0.77 TDP1 (0.30) TDP1
SCHEMBL14975305 0.77 EPHX1 (0.32) TDP1
SCHEMBL14975569 0.76 MAPT (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3204159-A1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS W.R. Grace & CO. - CONN. (US) 2017-08-16 EP disclosed
WO-2016057634-A1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS BASF CORPORATION (US) 2016-04-14 WO disclosed
EP-2539375-A2 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF Corporation (US) 2013-01-02 EP disclosed
WO-2011106480-A2 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CORPORATION (US) 2011-09-01 WO disclosed