⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15731315 | 0.73 | — | — | |
| SCHEMBL20783240 | 0.71 | — | — | |
| SCHEMBL711852 | 0.69 | — | — | |
| SCHEMBL16297236 | 0.69 | — | — | |
| SCHEMBL19809661 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL11425441 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL24393392 | 0.68 | — | — | |
| SCHEMBL9946967 | 0.67 | — | — | |
| SCHEMBL18102072 | 0.67 | — | — | |
| SCHEMBL19199553 | 0.67 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111582-A1 | AZA-TETRACYCLIC OXAZEPINE INHIBITORS OF KRAS-G12D | GENENTECH, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| WO-2024039858-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| WO-2023284837-A1 | ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | 四川海思科制药有限公司 | 2023-01-19 | — | — | WO | disclosed |