SCHEMBL24913588

SCHEMBL24913588

CC(C)(C)c1cc2[nH]c(-c3ccccn3)nn2n1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 7/20 0.44
CBFB Q13951 6/20 0.44
METAP1 P53582 6/20 0.44
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
PKM P14618 3/20 0.43
KDM4E B2RXH2 2/20 0.40
BTK Q06187 1/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
HPGD P15428 1/20 0.37
MTOR P42345 1/20 0.37
NPY5R Q15761 2/20 0.37
RUNX1 Q01196 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13325529 0.77 NPY5R (0.48) METAP2CBFBMETAP1NPC1RAB9A
SCHEMBL14074645 0.75 TNKS (0.40) NPC1RAB9ALMNASMN1; SMN2MAPT
SCHEMBL14440284 0.72 HPGD (0.43) NPC1RAB9AKDM4ELMNAMAPT
SCHEMBL6922845 0.71 SMN1; SMN2 (0.38) NPC1RAB9APKMKDM4ELMNA
SCHEMBL21851792 0.71 METAP2 (0.43) METAP2CBFBMETAP1NPC1RAB9A
SCHEMBL21851740 0.71 L3MBTL1 (0.39) METAP2CBFBMETAP1NPC1RAB9A
SCHEMBL30938483 0.71 NPC1 (0.41) METAP2NPC1RAB9AKDM4EBTK
SCHEMBL12910592 0.69 KDM4E (0.34) KDM4E
SCHEMBL15295087 0.68 KDM4E (0.44) METAP2CBFBMETAP1NPC1RAB9A
SCHEMBL14198996 0.65 KDM4E (0.31) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023286555-A1 SURFACE MODIFIER, LAMINATE, METHOD FOR FORMING METAL WIRING PATTERN, AND METHOD FOR PRODUCING PRINTED WIRING BOARD コニカミノルタ株式会社 2023-01-19 WO disclosed