Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31062032 | 1.00 | CA1 (0.48) | CA1CA2CA7CA9CA14 | |
| SCHEMBL24914042 | 0.96 | CA1 (0.52) | CA1CA2CA7CA9CA14 | |
| SCHEMBL30789170 | 0.96 | CA1 (0.52) | CA1CA2CA7CA9CA14 | |
| SCHEMBL25668992 | 0.92 | HDAC8 (0.44) | CA1CA2CA7CA9CA14 | |
| SCHEMBL30368448 | 0.92 | HDAC8 (0.44) | CA1CA2CA7CA9CA14 | |
| SCHEMBL31013763 | 0.89 | CA1 (0.44) | CA1CA2CA7CA9CA14 | |
| SCHEMBL30156656 | 0.88 | SPR (0.54) | CA1CA2CA7CA9CA14 | |
| SCHEMBL25669032 | 0.88 | SPR (0.54) | CA1CA2CA7CA9CA14 | |
| SCHEMBL31013684 | 0.86 | CA1 (0.48) | CA1CA2CA7CA9CA14 | |
| SCHEMBL24914041 | 0.85 | QRFPR (0.45) | GPR183CHRNA7KMT2ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002165-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2023-01-26 | — | — | WO | disclosed |