Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30156670 | 1.00 | PTGER1 (0.42) | PTGER1MAP4K4NR4A2PTGER4PTGER3 | |
| SCHEMBL25668954 | 0.90 | SPR (0.49) | HSP90AA1SPRHSP90AB1 | |
| SCHEMBL30368420 | 0.90 | SPR (0.49) | HSP90AA1SPRHSP90AB1 | |
| SCHEMBL30368246 | 0.90 | LMNA (0.48) | HSP90AA1NPC1HPGDRAB9AHSD17B10 | |
| SCHEMBL25668990 | 0.90 | LMNA (0.48) | HSP90AA1NPC1HPGDRAB9AHSD17B10 | |
| SCHEMBL24913808 | 0.90 | BRD4 (0.49) | HSP90AA1HSP90AB1MRGPRX4MEN1KMT2A | |
| SCHEMBL30789157 | 0.90 | BRD4 (0.49) | HSP90AA1HSP90AB1MRGPRX4MEN1KMT2A | |
| SCHEMBL24913807 | 0.90 | MRGPRX4 (0.44) | NR4A2HSP90AA1MRGPRX4NPC1TP53 | |
| SCHEMBL30789174 | 0.89 | BRD4 (0.48) | HSP90AA1SPRHSP90AB1HSD17B10 | |
| SCHEMBL30368461 | 0.87 | HSP90AA1 (0.41) | PTGER1HSP90AA1SPRHSP90AB1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693507-A | Inhibitor compounds | 奈奥芬莱有限公司 | 2024-03-12 | — | — | CN | disclosed |
| WO-2023002165-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2023-01-26 | — | — | WO | disclosed |