SCHEMBL24914589

SCHEMBL24914589

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-n4c5ccccc5c5ccc6c(c7ccccc7n6-c6cccc7c6oc6ccccc67)c54)n3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.33
TSHR P16473 5/20 0.33
LMNA P02545 4/20 0.32
KDM4E B2RXH2 3/20 0.32
HSD17B10 Q99714 3/20 0.32
MAPK1 P28482 2/20 0.32
ALDH1A1 P00352 5/20 0.31
POLB P06746 2/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 3/20 0.31
MEN1 O00255 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
ALOX12 P18054 1/20 0.31
USP2 O75604 1/20 0.31
HTT P42858 1/20 0.31
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20988689 0.98 MAPT (0.34) MAPTTSHRLMNAKDM4EHSD17B10
SCHEMBL24914600 0.97 MAPT (0.34) MAPTTSHRLMNAKDM4EHSD17B10
SCHEMBL24914585 0.95 MAPT (0.32) MAPTTSHRLMNAKDM4EHSD17B10
SCHEMBL20988536 0.95 MAPT (0.35) MAPTTSHRLMNAKDM4EHSD17B10
SCHEMBL17809146 0.93 MAPT (0.37) MAPTTSHRLMNAKDM4EHSD17B10
SCHEMBL24914531 0.92 MAPT (0.32) MAPTTSHRLMNAKDM4EHSD17B10
SCHEMBL17809393 0.92 MAPT (0.33) MAPTTSHRLMNAKDM4EHSD17B10
SCHEMBL21365781 0.91 MAPT (0.34) MAPTTSHRLMNAKDM4EHSD17B10
SCHEMBL24914776 0.91 TSHR (0.36) MAPTTSHRLMNAKDM4EHSD17B10
SCHEMBL17809139 0.91 MAPT (0.38) MAPTTSHRLMNAKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, SOD1 MAPT 2262/4885TSHR 4718/4885LMNA 4323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.