SCHEMBL2491463

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2492230	0.86	GCGR (0.38)	GCGRUSP7DHFRHEXAHEXB
	SCHEMBL28769956	0.84	USP7 (0.47)	GCGRUSP7ESR2ESR1DHFR
	SCHEMBL2492131	0.83	GCGR (0.45)	GCGRDHFR
	SCHEMBL9579775	0.78	GCGR (0.41)	GCGRUSP7ESR2ESR1DHFR
	SCHEMBL7108430	0.78	GCGR (0.41)	GCGRUSP7ESR2ESR1DHFR
	SCHEMBL30234292	0.78	ESR2 (0.53)	GCGRUSP7ESR2ESR1DHFR
	SCHEMBL2201812	0.78	ESR2 (0.53)	GCGRUSP7ESR2ESR1DHFR
	SCHEMBL28518728	0.77	GCGR (0.38)	GCGRUSP7ESR2ESR1DHFR
	Formaldehyde SCHEMBL29141443	0.77	ESR2 (0.49)	GCGRUSP7ESR2ESR1KDM4E
	SCHEMBL4870784	0.76	LMNA (0.39)	ESR2PTGS1PTGS2BRD4BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.