SCHEMBL4870784

SCHEMBL4870784

[CH2]c1ccc(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
BACE1 P56817 1/20 0.37
ALOX5 P09917 1/20 0.37
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
BCL2L1 Q07817 1/20 0.36
CYP2A6 P11509 1/20 0.36
MAPK1 P28482 1/20 0.36
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
BRD4 O60885 1/20 0.33
BRD2 P25440 1/20 0.33
ESR2 Q92731 1/20 0.33
CTRC Q99895 2/20 0.32
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL608536 0.84 ALDH1A1 (0.50) LMNAMAPTHTTBACE1ALOX5
SCHEMBL6125578 0.84 LMNA (0.37) LMNAMAPTHTTBACE1ALOX5
Biphenyl SCHEMBL28876393 0.82 ALDH1A1 (0.56) LMNAMAPTHTTBACE1ALOX5
SCHEMBL14390391 0.82 LMNA (0.48) LMNAMAPTHTTBACE1ALOX5
SCHEMBL28710407 0.82 LMNA (0.48) LMNAMAPTHTTBACE1ALOX5
Water SCHEMBL28835132 0.82 LMNA (0.48) LMNAMAPTHTTBACE1ALOX5
SCHEMBL2786541 0.81 ALDH1A1 (0.41) LMNAMAPTHTTBACE1ALDH1A1
SCHEMBL2490178 0.80 BRD4 (0.38) LMNAMAPTHTTBACE1ALOX5
SCHEMBL2489466 0.80 ALOX5AP (0.35) LMNAMAPTHTTBACE1ALOX5
SCHEMBL2492329 0.80 HDAC4 (0.45) LMNAMAPTHTTBACE1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284526-A Reactive anion chain transfer polymerization method for synthesizing low molecular weight polymer 大连理工大学 2023-06-23 CN claimed
EP-0309794-A2 No-post-cure method of curing polyacrylate polymers Zeon Chemicals USA, Inc. (US) 1989-04-05 EP claimed
JP-62236849-A None JP disclosed
JP-59016900-A None JP disclosed
CN-118369596-A Resin composition for lens, cured product for lens, and lens 三井化学株式会社 2024-07-19 CN disclosed
CN-118215887-A Composition for forming resist underlayer film 日产化学株式会社 2024-06-18 CN disclosed
CN-118076485-A Laminate, epoxy film, and wound body 三菱化学株式会社 2024-05-24 CN disclosed
CN-117203299-A High-temperature separable conductive adhesive for curing epoxy resin and solar cell module 大洲电子材料株式会社 2023-12-08 CN disclosed
CN-116284526-A Reactive anion chain transfer polymerization method for synthesizing low molecular weight polymer 大连理工大学 2023-06-23 CN disclosed
US-20230157168-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-18 US disclosed
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-11 US disclosed
US-5176984-A With a cationic dye, photoinitiator THE MEAD CORPORATION (US) 1993-01-05 US disclosed
WO-1992012199-A1 CURING FLUOROCARBON ELASTOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-07-23 WO disclosed
WO-1992003136-A1 QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS ABBOTT LABORATORIES (US) 1992-03-05 WO disclosed
EP-0408858-A1 Copolymers for use in high solids, low volatile organic content coatings BASF Corporation (US) 1991-01-23 EP disclosed
EP-0337207-A2 Preparation process of aromatic polycarbonates, aromatic polyestercarbonates and aromatic polyesters BAYER AG (DE) 1989-10-18 EP disclosed
EP-0309622-A1 Method for reducing build up of electrostatic charges on transparent synthetic macromolecular materials selected from polymethyl methycrylate or polycarbonate Takemoto Yushi Kabushiki Kaisha (JP) 1989-04-05 EP disclosed
JP-S62236849-A VULCANIZABLE ACRYLATE ELASTOMER COMPOSITION NIPPON ZEON CO LTD 1987-10-16 JP disclosed
JP-S5916900-A OLIGOSACCHARIDE AND ITS PREPARATION KANTO ISHI PHARMA CO LTD 1984-01-28 JP disclosed
EP-0008837-B1 RADIATION CURABLE LIQUID COATING COMPOSITION BASED ON AN EPOXY TERMINATED COMPOUND AND A PROCESS FOR COATING A SUBSTRATE WITH SUCH A COMPOSITION AKZO N.V. (NL) 1982-05-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME NECTIN4, SOD1, ELAVL1 LMNA 4413/4885MAPT 2415/4885HTT 2713/4885
US-20230157168-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, EPCAM, NECTIN4 LMNA 4342/4885MAPT 2279/4885HTT 3703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.