Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24914497 | 0.94 | POLQ (0.38) | POLQHDAC8SMN1; SMN2CTSSKCNK3 | |
| SCHEMBL24914949 | 0.92 | POLQ (0.33) | POLQHDAC8SMN1; SMN2CTSSHDAC1 | |
| SCHEMBL24914487 | 0.91 | POLQ (0.34) | POLQHDAC8CTSSKCNK3KCNK9 | |
| SCHEMBL29028501 | 0.87 | GPBAR1 (0.34) | HDAC8PTGES | |
| SCHEMBL29704540 | 0.87 | HDAC8 (0.36) | HDAC8HDAC1HDAC6 | |
| SCHEMBL21705019 | 0.87 | HDAC8 (0.36) | HDAC8HDAC1HDAC6 | |
| SCHEMBL29381908 | 0.87 | HDAC8 (0.36) | HDAC8HDAC1HDAC6 | |
| SCHEMBL23716778 | 0.86 | POLQ (0.38) | POLQHDAC8SMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL31348975 | 0.86 | SMN1; SMN2 (0.33) | HDAC8SMN1; SMN2KCNK3KCNK9PTGES | |
| SCHEMBL29114027 | 0.85 | PTGES (0.33) | HDAC8PTGESHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284645-A1 | AMIDE COMPOUND AND USE THEREOF | 沈阳化工大学 | 2023-01-19 | — | — | WO | disclosed |