Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 10/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24914413 | 1.00 | CLPP (0.49) | CLPPDDB1CRBNENPP2DRD2 | |
| SCHEMBL30130122 | 1.00 | CLPP (0.49) | CLPPDDB1CRBNENPP2DRD2 | |
| SCHEMBL24914414 | 0.94 | CLPP (0.47) | CLPPDDB1CRBNENPP2 | |
| SCHEMBL24914797 | 0.93 | CLPP (0.50) | CLPPDDB1CRBNENPP2DRD2 | |
| SCHEMBL24914704 | 0.93 | CLPP (0.50) | CLPPDDB1CRBNENPP2DRD2 | |
| SCHEMBL24914395 | 0.91 | CLPP (0.55) | CLPPDDB1CRBNENPP2DRD2 | |
| SCHEMBL24914417 | 0.90 | DRD2 (0.50) | CLPPDDB1CRBNENPP2DRD2 | |
| SCHEMBL24914443 | 0.90 | DRD2 (0.50) | CLPPDDB1CRBNENPP2DRD2 | |
| SCHEMBL30130185 | 0.90 | DRD2 (0.50) | CLPPDDB1CRBNENPP2DRD2 | |
| SCHEMBL24914723 | 0.90 | CLPP (0.54) | CLPPDRD2DRD4DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284807-A1 | COMPOUND CONTAINING TETRAHYDRONAPHTHYRIDONE OR TETRAHYDROPYRIDOPYRIMIDINONE SKELETON, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2023-01-19 | — | — | WO | disclosed |