SCHEMBL2491582

SCHEMBL2491582

O=S(OCC(Cl)Cl)OCC(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2491584 0.77
SCHEMBL27535707 0.73 ALDH1A1 (0.33) CYP2C19
SCHEMBL10603314 0.71
SCHEMBL10925810 0.69
SCHEMBL28821954 0.69 CYP2C19 (0.33) CYP2C19
SCHEMBL777223 0.69 ALDH1A1 (0.46) CYP2C19
SCHEMBL4126499 0.65 CYP2C19 (0.36) CYP2C19
SCHEMBL22440709 0.65 MAPK1 (0.40) CYP2C19
SCHEMBL10926213 0.64
SCHEMBL1576607 0.63 CYP2C19 (0.35) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10196649-B2 Method for increasing pathogen resistance in plants UNIVERSIDAD POLITECNICA DE MADRID (ES) 2019-02-05 US disclosed
US-20160237450-A1 METHOD FOR ENHANCING DROUGHT TOLERANCE IN PLANTS PLANT RESPONSE BIOTECH S.L. (ES) 2016-08-18 US disclosed
EP-3032952-A1 METHODS FOR ENHANCING DROUGHT TOLERANCE IN PLANTS Plant Response Biotech, S.L. (ES) 2016-06-22 EP disclosed
US-20160108424-A1 METHOD FOR INCREASING PATHOGEN RESISTANCE IN PLANTS UNIVERSIDAD POLITECNICA DE MADRID (ES) 2016-04-21 US disclosed
US-9085776-B2 Method for enhancing drought tolerance in plants PLANT RESPONSE BIOTECH S.L. (ES) 2015-07-21 US disclosed
WO-2015092576-A1 IMPROVED PROCESS FOR THE PRODUCTION OF GAMMA-AMINOBUTYRIC ACID (GABA) BASF SE (DE) 2015-06-25 WO disclosed
WO-2015092599-A1 IMPROVED PROCESS FOR THE PRODUCTION OF GAMMA-AMINOBUTYRIC ACID (GABA) BASF SE (DE) 2015-06-25 WO disclosed
US-20150052632-A1 METHOD FOR ENHANCING DROUGHT TOLERANCE IN PLANTS Plant Response, Inc. 2015-02-19 US disclosed
WO-2015022365-A1 METHODS FOR ENHANCING DROUGHT TOLERANCE IN PLANTS PLANT RESPONSE BIOTECH, S.L. (ES) 2015-02-19 WO disclosed
WO-2014095990-A1 METHOD FOR INCREASING PATHOGEN RESISTANCE IN PLANTS UNIVERSIDAD POLITECNICA DE MADRID (ES) 2014-06-26 WO disclosed
US-20090222944-A1 Use Of Stomatin (STM1) Polynucleotides For Achieving A Pathogen Resistance In Plants BASF PLANT SCIENCE GMBH (DE) 2009-09-03 US disclosed
US-20090156485-A1 METHOD FOR COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS BASE SE (DE) 2009-06-18 US disclosed
EP-2057273-A2 USE OF SUBTILISIN (RNR9) POLYNUCLEOTIDES FOR ACHIEVING A PATHOGEN RESISTANCE IN PLANTS BASF Plant Science GmbH (DE) 2009-05-13 EP disclosed
US-20090098076-A1 Method For the Production of a Keratin-Binding Effector Molecule BASF SE (DE) 2009-04-16 US disclosed
US-20090099075-A1 Chimeric Keratin-Binding Effector Proteins BASF SE (DE) 2009-04-16 US disclosed
US-20090098074-A1 Keratin-Binding Effector Molecules Containing Reactive Dyes BASF SE (DE) 2009-04-16 US disclosed
EP-1979484-A1 USE OF STOMATIN (STM1) POLYNUCLEOTIDES FOR ACHIEVING A PATHOGEN RESISTANCE IN PLANTS BASF Plant Science GmbH (DE) 2008-10-15 EP disclosed
WO-2008087141-A2 USE OF SUBTILISIN (RNR9) POLYNUCLEOTIDES FOR ACHIEVING A PATHOGEN RESISTANCE IN PLANTS BASF PLANT SCIENCE GMBH (DE) 2008-07-24 WO disclosed
US-20080120740-A1 Novel Nucleic Acid Sequences and Their Use in Methods for Achieving a Pathogenic Resistance in Plants BASF PLANT SCIENCE GMBH (DE) 2008-05-22 US disclosed
WO-2007080143-A1 USE OF STOMATIN (STM1) POLYNUCLEOTIDES FOR ACHIEVING A PATHOGEN RESISTANCE IN PLANTS BASF PLANT SCIENCE GMBH (DE) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098074-A1 Keratin-Binding Effector Molecules Containing Reactive Dyes KRT18, KLK3, KLKB1 CYP2C19 4643/4885
US-20090156485-A1 METHOD FOR COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS KRT18, KRTCAP2, CUTA CYP2C19 4730/4885
US-20090099075-A1 Chimeric Keratin-Binding Effector Proteins KRT18, KRTCAP2, CKAP4 CYP2C19 4858/4885
US-20090098076-A1 Method For the Production of a Keratin-Binding Effector Molecule KRT18, KRTCAP2, CUTA CYP2C19 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.