Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 12/20 | 0.57 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30054375 | 1.00 | WDR5 (0.57) | WDR5EGLN1HDAC3HDAC4HDAC1 | |
| SCHEMBL24886259 | 0.86 | WDR5 (0.57) | WDR5EGLN1GAA | |
| SCHEMBL30190397 | 0.86 | WDR5 (0.57) | WDR5EGLN1GAA | |
| SCHEMBL29923484 | 0.81 | EGLN1 (0.62) | EGLN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24916112 | 0.81 | EGLN1 (0.62) | EGLN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30054337 | 0.80 | EGLN1 (0.56) | EGLN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27167342 | 0.80 | EGLN1 (0.56) | EGLN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24916482 | 0.80 | EGLN1 (0.51) | EGLN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29923666 | 0.80 | EGLN1 (0.51) | EGLN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30054435 | 0.76 | EGLN1 (0.51) | EGLN1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | WDR5 1/4885EGLN1 1068/4885HDAC3 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.