Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | GBA1 | P04062 | 6/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24894084 | 0.99 | EPHX2 (0.51) | EPHX2DRD2HRH4HRH3CYP19A1 | |
| SCHEMBL20631155 | 0.91 | EPHX2 (0.53) | EPHX2DRD2HRH4HRH3CYP19A1 | |
| SCHEMBL18768818 | 0.90 | EPHX2 (0.46) | EPHX2DRD2 | |
| SCHEMBL25978166 | 0.87 | EPHX2 (0.50) | EPHX2DRD2HRH4HRH3CYP19A1 | |
| SCHEMBL20631166 | 0.86 | DRD2 (0.55) | EPHX2DRD2HRH4HRH3CYP19A1 | |
| SCHEMBL17776309 | 0.86 | CSNK2A1 (0.41) | EPHX2DRD2 | |
| SCHEMBL22060194 | 0.86 | EPHX2 (0.53) | EPHX2DRD2HRH4HRH3CYP19A1 | |
| SCHEMBL25978169 | 0.86 | EPHX2 (0.48) | EPHX2DRD2HRH4HRH3CYP19A1 | |
| SCHEMBL24450930 | 0.85 | DGAT1 (0.39) | DRD2GBA1 | |
| SCHEMBL21118027 | 0.84 | DGAT1 (0.52) | EPHX2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |