⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089159 | 0.82 | TSHR (0.35) | — | |
| SCHEMBL11312264 | 0.73 | — | — | |
| SCHEMBL19871282 | 0.71 | HTR2C (0.32) | — | |
| SCHEMBL24916693 | 0.70 | — | — | |
| SCHEMBL14877470 | 0.69 | IMPDH2 (0.33) | — | |
| SCHEMBL28919639 | 0.67 | IMPDH2 (0.32) | — | |
| SCHEMBL19605886 | 0.65 | KDM4E (0.36) | — | |
| SCHEMBL13316831 | 0.63 | — | — | |
| SCHEMBL15258088 | 0.63 | IMPDH2 (0.30) | — | |
| SCHEMBL847735 | 0.63 | TAS1R3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |