Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CD69 | Q07108 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | SELL | P14151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25343369 | 0.79 | MAPK1 (0.71) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL25344300 | 0.79 | MAPK1 (0.71) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL17208462 | 0.78 | MAPK1 (0.57) | MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL24917518 | 0.78 | OGA (0.36) | MAPK1ALDH1A1THRBCD69OGA | |
| SCHEMBL9314298 | 0.78 | LGALS8 (0.42) | MAPK1LGALS8LGALS3ALDH1A1THRB | |
| SCHEMBL9314309 | 0.78 | LGALS8 (0.42) | MAPK1LGALS8LGALS3ALDH1A1THRB | |
| SCHEMBL9314303 | 0.78 | LGALS8 (0.42) | MAPK1LGALS8LGALS3ALDH1A1THRB | |
| SCHEMBL7893025 | 0.76 | MAPK1 (0.38) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL7893027 | 0.76 | MAPK1 (0.38) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL7893023 | 0.76 | MAPK1 (0.38) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |