Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CD69 | Q07108 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PYGB | P11216 | 1/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314303 | 1.00 | LGALS8 (0.42) | LGALS8ALDH1A1THRBCD69MAPK1 | |
| SCHEMBL9314298 | 1.00 | LGALS8 (0.42) | LGALS8ALDH1A1THRBCD69MAPK1 | |
| SCHEMBL7148353 | 0.86 | CA1 (0.33) | LGALS8ALDH1A1THRBCD69MAPK1 | |
| SCHEMBL9314131 | 0.81 | OGA (0.41) | ALDH1A1THRBCD69MAPK1OGA | |
| SCHEMBL21686200 | 0.81 | MGAM (0.42) | LGALS8MGAMSIOGACA2 | |
| SCHEMBL9314127 | 0.81 | OGA (0.41) | ALDH1A1THRBCD69MAPK1OGA | |
| SCHEMBL14669268 | 0.81 | OGA (0.41) | ALDH1A1THRBCD69MAPK1OGA | |
| SCHEMBL20812843 | 0.81 | OGA (0.41) | ALDH1A1THRBCD69MAPK1OGA | |
| SCHEMBL9314136 | 0.81 | OGA (0.41) | ALDH1A1THRBCD69MAPK1OGA | |
| SCHEMBL7893025 | 0.81 | MAPK1 (0.38) | LGALS8ALDH1A1THRBCD69MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332756-A | Angiogenesis inhibitor, antitumor | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-07-26 | — | — | US | disclosed |
| EP-0527042-A2 | 3-deoxy-mannosamine derivatives and process for their preparation | PHARMACIA S.p.A. (IT) | 1993-02-10 | — | — | EP | disclosed |