Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181821 | 1.00 | MGLL (0.47) | MGLLPTGS1PTGS2FAAHHPGD | |
| SCHEMBL21648869 | 0.99 | MGLL (0.45) | MGLLPTGS1PTGS2FAAHHPGD | |
| SCHEMBL20272155 | 0.93 | MGLL (0.45) | MGLLPTGS1PTGS2FAAHHPGD | |
| SCHEMBL30180642 | 0.92 | MGLL (0.47) | MGLLPTGS1PTGS2HPGDALDH1A1 | |
| SCHEMBL45879 | 0.89 | MGLL (0.47) | MGLLPTGS1PTGS2FAAHHPGD | |
| SCHEMBL19703723 | 0.89 | MGLL (0.56) | MGLLPTGS1PTGS2FAAHHPGD | |
| SCHEMBL13401579 | 0.89 | MGLL (0.47) | MGLLPTGS1PTGS2FAAHHPGD | |
| SCHEMBL17740049 | 0.89 | MGLL (0.56) | MGLLPTGS1PTGS2FAAHHPGD | |
| SCHEMBL24621630 | 0.89 | MGLL (0.47) | MGLLPTGS1PTGS2FAAHHPGD | |
| SCHEMBL13311214 | 0.89 | MGLL (0.47) | MGLLPTGS1PTGS2FAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |