Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916800 | 0.92 | MGLL (0.47) | MGLLSMN1; SMN2GSK3AGSK3BALDH1A1 | |
| SCHEMBL12181821 | 0.92 | MGLL (0.47) | MGLLSMN1; SMN2GSK3AGSK3BALDH1A1 | |
| SCHEMBL21648869 | 0.90 | MGLL (0.45) | MGLLSMN1; SMN2GSK3AGSK3BALDH1A1 | |
| SCHEMBL277801 | 0.90 | SMN1; SMN2 (0.42) | MGLLSMN1; SMN2GSK3AGSK3BTSHR | |
| SCHEMBL20272155 | 0.90 | MGLL (0.45) | MGLLSMN1; SMN2GSK3AGSK3BALDH1A1 | |
| SCHEMBL15143431 | 0.89 | MGLL (0.47) | MGLLSMN1; SMN2GSK3AGSK3BTSHR | |
| SCHEMBL16329201 | 0.89 | MGLL (0.47) | MGLLSMN1; SMN2GSK3AGSK3BTSHR | |
| SCHEMBL24136290 | 0.89 | MGLL (0.47) | MGLLSMN1; SMN2GSK3AGSK3BTSHR | |
| SCHEMBL13311294 | 0.89 | MGLL (0.47) | MGLLSMN1; SMN2GSK3AGSK3BTSHR | |
| SCHEMBL24591874 | 0.89 | MGLL (0.47) | MGLLSMN1; SMN2GSK3AGSK3BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370157-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |