Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 7/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26590894 | 0.84 | EGLN2 (0.34) | DOT1LEGLN2TMPRSS2 | |
| SCHEMBL26590912 | 0.83 | DOT1L (0.34) | RIPK1DOT1L | |
| SCHEMBL24313030 | 0.83 | DOT1L (0.34) | RIPK1DOT1LTMPRSS2 | |
| SCHEMBL26590914 | 0.82 | DOT1L (0.32) | RIPK1DOT1LTMPRSS2 | |
| SCHEMBL24916998 | 0.82 | DOT1L (0.33) | RIPK1DOT1LTMPRSS2 | |
| SCHEMBL24917360 | 0.82 | DOT1L (0.33) | RIPK1DOT1LTMPRSS2 | |
| SCHEMBL26590911 | 0.82 | RIPK1 (0.33) | RIPK1DOT1LEGLN2TMPRSS2 | |
| SCHEMBL26590909 | 0.81 | DOT1L (0.31) | RIPK1DOT1LTMPRSS2 | |
| SCHEMBL24917023 | 0.81 | CTSL (0.31) | RIPK1 | |
| SCHEMBL24312592 | 0.80 | TMPRSS2 (0.46) | RIPK1EGLN2MGLLTMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | SLC29A2, SLC29A1, PNP | RIPK1 2571/4885DOT1L 3715/4885EGLN2 2347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.