Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522462 | 0.87 | KMT2A (0.43) | KMT2AMEN1TSHRVCAM1GAA | |
| SCHEMBL21049231 | 0.87 | KMT2A (0.43) | KMT2AMEN1TSHRVCAM1GAA | |
| SCHEMBL25495837 | 0.87 | KMT2A (0.43) | KMT2AMEN1TSHRVCAM1GAA | |
| SCHEMBL18913619 | 0.86 | DGKA (0.47) | KMT2ATSHRDGKALMNA | |
| SCHEMBL4953772 | 0.85 | KMT2A (0.44) | KMT2AMEN1TSHRVCAM1DGKA | |
| SCHEMBL17337909 | 0.85 | KMT2A (0.48) | KMT2AMEN1TSHRVCAM1DGKA | |
| SCHEMBL24916959 | 0.83 | MEN1 (0.31) | KMT2AMEN1 | |
| SCHEMBL23813738 | 0.80 | PAOX (0.42) | KMT2AMEN1TSHRVCAM1DGKA | |
| SCHEMBL22271695 | 0.80 | DGKA (0.52) | KMT2AMEN1TSHRDGKALMNA | |
| SCHEMBL22463686 | 0.80 | DGKA (0.52) | KMT2AMEN1TSHRDGKALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |