SCHEMBL2491792

SCHEMBL2491792

NC(=O)CCc1ccccc1C(O)=S

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
FOLH1 Q04609 1/20 0.44
ALDH1A1 P00352 4/20 0.42
LMNA P02545 3/20 0.42
ADRB2 P07550 1/20 0.41
MTNR1A P48039 1/20 0.39
HTT P42858 2/20 0.38
MAPT P10636 2/20 0.38
NR4A2 P43354 1/20 0.38
MPO P05164 1/20 0.38
KDM4E B2RXH2 2/20 0.38
HPGD P15428 1/20 0.38
HMGB1 P09429 1/20 0.38
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6800544 0.85 FOLH1 (0.61) KMT2AFOLH1ALDH1A1LMNAMTNR1A
SCHEMBL9627316 0.81 MAPT (0.50) KMT2AFOLH1ALDH1A1LMNAMAPT
SCHEMBL9321175 0.80 MTNR1A (0.47) ALDH1A1LMNAMTNR1ANR4A2MPO
SCHEMBL2491789 0.80 FOLH1 (0.46) KMT2AFOLH1ALDH1A1LMNAADRB2
SCHEMBL27417768 0.78 FFAR1 (0.52) KMT2AALDH1A1LMNAADRB2HTT
SCHEMBL3571210 0.77 ALDH1A1 (0.45) KMT2AFOLH1ALDH1A1LMNAMTNR1A
SCHEMBL9030516 0.76 ALDH1A1 (0.73) KMT2AALDH1A1LMNAMTNR1AHTT
SCHEMBL10822489 0.76 MTNR1A (0.42) ALDH1A1LMNAMTNR1ANR4A2MPO
SCHEMBL7759364 0.75 TDP1 (0.44) KMT2AFOLH1ALDH1A1LMNAADRB2
SCHEMBL4735612 0.74 ALDH1A1 (0.54) KMT2AFOLH1ALDH1A1LMNAADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011195453-A IMMUNE-MEASURING REAGENT MORINAGA & CO LTD 2011-10-06 JP disclosed