Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | MPO | P05164 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945686 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL2945687 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL4309022 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL10701837 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL10701840 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL4309019 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL31036050 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL30661929 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL27577681 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL27367040 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383881-B1 | PHOSPHINIC PEPTIDE DERIVATIVES FOR USE AS MMP-12 INHIBITORS | DSM IP ASSETS BV (NL) | 2019-07-31 | — | — | EP | claimed |
| JP-2011195451-A | PEPTIDE | FUKUOKA UNIV | 2011-10-06 | — | — | JP | disclosed |