Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661929 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EMAPTKMT2AL3MBTL1 | |
| SCHEMBL27829210 | 0.88 | KDM4E (0.56) | SMN1; SMN2KDM4EMAPTKMT2AL3MBTL1 | |
| SCHEMBL2945686 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4EMAPTKMT2AL3MBTL1 | |
| SCHEMBL2945687 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4EMAPTKMT2AL3MBTL1 | |
| SCHEMBL10701837 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTKMT2AL3MBTL1 | |
| SCHEMBL2491934 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTKMT2AL3MBTL1 | |
| SCHEMBL4309022 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTKMT2AL3MBTL1 | |
| SCHEMBL4309019 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTKMT2AL3MBTL1 | |
| SCHEMBL10701840 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTKMT2AL3MBTL1 | |
| SCHEMBL28069324 | 0.83 | HTR2C (0.63) | KDM4EMAPTKMT2AMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776555-A | Bifunctional D-amino acid modified opioid peptide compound and synthesis method and application thereof | 王锐 | 2020-02-11 | — | — | CN | disclosed |
| CN-108025574-B | Thermal recording medium | 三光株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-108025574-A | Thermal recording medium | 三光株式会社 | 2018-05-11 | — | — | CN | disclosed |
| CN-106967151-A | The endomorphins of many Sites Combination modifications are like thing and its synthesis and application | 兰州大学 | 2017-07-21 | — | — | CN | disclosed |
| CN-1646910-A | Method for determining leukemia, preleukemia or non-leukemia malignant blood disease and diagnostic agent | UNIV TOKAI KYOWA HAKKO KOGYO K (JP) | 2005-07-27 | — | — | CN | disclosed |
| CN-1473145-A | Method for separating optical isomers of amino acid derivatives | ��ʽ�����ɽ | 2004-02-04 | — | — | CN | disclosed |
| CN-1066150-C | Bridged indoles as matrix metalloprotease inhibitors | SYNTEX INC (US) | 2001-05-23 | — | — | CN | disclosed |
| CN-1180358-A | Bridged indoles as matrix metalloprotease inhibitors | SYNTEX INC (US) | 1998-04-29 | — | — | CN | disclosed |