Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10820407 | 0.83 | ALOX15 (0.43) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL261608 | 0.82 | ALOX15 (0.42) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| Tiformin SCHEMBL828055 | 0.81 | ALOX15 (0.47) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL12825069 | 0.79 | ALOX15 (0.41) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| Tiformin SCHEMBL9772228 | 0.79 | ALOX15 (0.46) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL10287837 | 0.78 | PAOX (0.50) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL9809324 | 0.78 | ALOX15 (0.42) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| Acetic Acid SCHEMBL5691675 | 0.77 | MEN1 (0.53) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL33717 | 0.77 | PRMT1 (0.50) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL14598288 | 0.77 | KDM4E (0.65) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | disclosed |