Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22059792 | 0.85 | RXFP1 (0.38) | RXFP1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL12840774 | 0.81 | POLB (0.53) | RXFP1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL6015468 | 0.78 | ALDH1A1 (0.38) | TDP1ALDH1A1THRBALOX15HSD17B10 | |
| SCHEMBL13514007 | 0.77 | PTPN1 (0.56) | TDP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL9911354 | 0.77 | MEN1 (0.50) | RXFP1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL18090988 | 0.77 | RXFP1 (0.47) | RXFP1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL12667382 | 0.76 | RXFP1 (0.46) | RXFP1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL2754828 | 0.75 | TDP1 (0.50) | RXFP1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL2971862 | 0.74 | TDP1 (0.54) | RXFP1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL9636849 | 0.74 | IDO1 (0.45) | ALDH1A1L3MBTL1LMNASMN1; SMN2NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006782-A1 | CONJUGATING REAGENTS AND CONJUGATES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2023-02-02 | — | — | WO | disclosed |