SCHEMBL9636849

SCHEMBL9636849

C=C(C)Cc1ccc(C(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.45
CNR2 P34972 1/20 0.42
NLRP3 Q96P20 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
ACACB O00763 1/20 0.39
PYCR1 P32322 1/20 0.38
RAB9A P51151 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11503253 1.00 IDO1 (0.45) IDO1CNR2NLRP3HDAC3HDAC4
SCHEMBL6015468 0.83 ALDH1A1 (0.38) MEN1KMT2AHTTSMN1; SMN2ALDH1A1
SCHEMBL24244099 0.83 IDO1 (0.45) IDO1CNR2NLRP3HDAC3HDAC4
SCHEMBL9420390 0.79 POLB (0.35) CNR2HTTLMNAESR1ESR2
SCHEMBL9420388 0.79 PTGS2 (0.61) KMT2AHTTLMNAESR1
SCHEMBL2309410 0.78 POLB (0.58) IDO1CNR2NLRP3HDAC3HDAC4
SCHEMBL9782634 0.77 NPC1 (0.46) IDO1CNR2RAB9AMEN1KMT2A
SCHEMBL9485643 0.77 ALDH1A1 (0.46) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL28498052 0.77 IDO1 (0.44) IDO1CNR2NLRP3HDAC3HDAC4
SCHEMBL23230257 0.77 LMNA (0.43) MEN1KMT2AHTTRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0294557-B1 PROCESS FOR THE PREPARATION OF 3-PHENYL-2-METHYLPROPANOL AND ITS PARA-SUBSTITUTED ALKYLIC DERIVATIVES HÜLS AKTIENGESELLSCHAFT (DE) 1992-07-08 EP disclosed
US-4642405-A POLYMERIZATION INHIBITORS HUELS AKTIENGESELLSCHAFT (DE) 1987-02-10 US disclosed
EP-0001809-A1 Synergetic insecticidal and acaricidal mixtures BASF Aktiengesellschaft (DE) 1979-05-16 EP disclosed