Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21105359 | 0.83 | CTSK (0.33) | MAPTALDH1A1MCL1LMNAPOLB | |
| SCHEMBL22834424 | 0.83 | BIRC2 (0.41) | — | |
| SCHEMBL9885918 | 0.81 | MAPT (0.33) | MAPTALDH1A1MCL1LMNAPOLB | |
| SCHEMBL28841656 | 0.78 | POLB (0.30) | POLB | |
| SCHEMBL20197728 | 0.78 | MCL1 (0.41) | MCL1 | |
| SCHEMBL9620366 | 0.77 | TSHR (0.42) | MAPTALDH1A1LMNACA1CA2 | |
| SCHEMBL27402976 | 0.75 | GAA (0.41) | MAPTALDH1A1MCL1LMNATNF | |
| SCHEMBL25517 | 0.75 | — | — | |
| SCHEMBL10110030 | 0.75 | — | — | |
| SCHEMBL10110049 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |