Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920554 | 0.88 | LMNA (0.50) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL24920531 | 0.88 | HSP90AB1 (0.56) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL24920540 | 0.85 | LMNA (0.47) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL16509723 | 0.83 | LMNA (0.52) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL25986172 | 0.82 | MAPT (0.54) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL12142330 | 0.82 | LMNA (0.45) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL13572986 | 0.82 | LMNA (0.45) | LMNAPOLBMAPTTP53HSP90AB1 | |
| SCHEMBL14094522 | 0.82 | HSP90AB1 (0.49) | LMNAPOLBMAPTTP53HSP90AB1 | |
| Hydrochloric Acid SCHEMBL1367050 | 0.81 | LMNA (0.44) | LMNAPOLBMAPTTP53HSP90AB1 | |
| Hydrochloric Acid SCHEMBL1543006 | 0.81 | LMNA (0.44) | LMNAPOLBMAPTTP53HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |