Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 7/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920547 | 0.87 | AOC3 (0.38) | AOC3RXRAGRIN1GRIN2BPDE10A | |
| SCHEMBL20745928 | 0.87 | NR1H2 (0.39) | AOC3MAP4K4EGFRCHRM4PDE10A | |
| SCHEMBL20745925 | 0.86 | AOC3 (0.35) | AOC3MAP4K4EGFRCHRM4PDE10A | |
| SCHEMBL24921022 | 0.85 | AOC3 (0.38) | AOC3RXRAGRIN1GRIN2B | |
| SCHEMBL24921790 | 0.84 | AOC3 (0.39) | AOC3RXRAGRIN1GRIN2B | |
| SCHEMBL24921046 | 0.81 | AOC3 (0.38) | AOC3EGFRRXRAGRIN1GRIN2B | |
| SCHEMBL24920527 | 0.80 | ACACB (0.44) | AOC3PDE10ARBP4TTR | |
| SCHEMBL24920546 | 0.80 | AOC3 (0.37) | AOC3EGFRRXRAGRIN1GRIN2B | |
| SCHEMBL24921040 | 0.79 | AOC3 (0.44) | AOC3RXRAGRIN1GRIN2BPDE10A | |
| SCHEMBL24921023 | 0.79 | AOC3 (0.44) | AOC3RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |