SCHEMBL24920547 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	AOC3	Q16853	2/20	0.38

▸	HCRTR1	O43613	6/20	0.35

▸	HCRTR2	O43614	6/20	0.35

▸	PDE10A	Q9Y233	2/20	0.35

▸	RXRA	P19793	4/20	0.34

▸	GRIN1	Q05586	4/20	0.34

▸	GRIN2B	Q13224	4/20	0.34

▸	ACACB	O00763	1/20	0.34

▸	PDCD1	Q15116	1/20	0.34

▸	CD274	Q9NZQ7	1/20	0.34

▸	RBP4	P02753	1/20	0.34

▸	TTR	P02766	1/20	0.34

▸	LRRK2	Q5S007	1/20	0.33

▸	NR1H2	P55055	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24920527	0.90	ACACB (0.44)	AOC3PDE10AACACBRBP4TTR
SCHEMBL24920529	0.87	AOC3 (0.36)	AOC3PDE10ARXRAGRIN1GRIN2B
SCHEMBL24921022	0.84	AOC3 (0.38)	AOC3HCRTR1HCRTR2RXRAGRIN1
SCHEMBL22262510	0.83	AOC3 (0.33)	AOC3HCRTR1HCRTR2PDE10AACACB
SCHEMBL24921790	0.83	AOC3 (0.39)	AOC3HCRTR1HCRTR2RXRAGRIN1
SCHEMBL20745928	0.81	NR1H2 (0.39)	AOC3HCRTR1HCRTR2PDE10ARBP4
SCHEMBL24921046	0.80	AOC3 (0.38)	AOC3HCRTR1HCRTR2PDE10ARXRA
SCHEMBL24920546	0.78	AOC3 (0.37)	AOC3HCRTR1HCRTR2RXRAGRIN1
SCHEMBL24921040	0.78	AOC3 (0.44)	AOC3PDE10ARXRAGRIN1GRIN2B
SCHEMBL24921023	0.78	AOC3 (0.44)	AOC3RXRAGRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023006097-A1	BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER	海创药业股份有限公司	2023-02-02	—	—	WO	disclosed