Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 6/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921022 | 0.82 | AOC3 (0.38) | AOC3HCRTR1HCRTR2RXRAGRIN1 | |
| SCHEMBL24921790 | 0.81 | AOC3 (0.39) | AOC3HCRTR1HCRTR2RXRAGRIN1 | |
| SCHEMBL24920529 | 0.80 | AOC3 (0.36) | AOC3RXRAGRIN1GRIN2BEGFR | |
| SCHEMBL24920547 | 0.78 | AOC3 (0.38) | AOC3NR1H2HCRTR1HCRTR2RXRA | |
| SCHEMBL20745925 | 0.78 | AOC3 (0.35) | AOC3NR1H2CA12CA1CA2 | |
| SCHEMBL24921046 | 0.77 | AOC3 (0.38) | AOC3HCRTR1HCRTR2RXRAGRIN1 | |
| SCHEMBL24920543 | 0.77 | DYRK1A (0.46) | AOC3 | |
| SCHEMBL24921023 | 0.76 | AOC3 (0.44) | AOC3CA12CA1CA2CA9 | |
| SCHEMBL24921040 | 0.76 | AOC3 (0.44) | AOC3CA12CA1CA2CA9 | |
| SCHEMBL24921025 | 0.75 | RXRA (0.39) | AOC3RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |