SCHEMBL24920638

SCHEMBL24920638

[N-]=[N+]=NCCOCCOCCOCCOCCC(=O)NCCCNC(=O)CN(CCNC(=O)CN(CCNC(=O)COCCOCCN)CCNC(=O)COCCOCCN)CCNC(=O)CN(CCNC(=O)COCCOCCN)CCNC(=O)COCCOCCN

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24920287 0.92 CA1 (0.30)
SCHEMBL24920285 0.89 CA1 (0.31)
SCHEMBL24920639 0.84 PLK1 (0.35) PLK1
SCHEMBL24920332 0.84 PLK1 (0.35) PLK1
SCHEMBL24920288 0.82 CA1 (0.34) PLK1
SCHEMBL24920234 0.81 TDP1 (0.36) PLK1
SCHEMBL24920229 0.81 TDP1 (0.36) PLK1
SCHEMBL24920307 0.80 TSHR (0.35) PLK1
SCHEMBL24920286 0.80 CA1 (0.36) PLK1
SCHEMBL19437438 0.80 CRBN (0.37) PLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006782-A1 CONJUGATING REAGENTS AND CONJUGATES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2023-02-02 WO disclosed