SCHEMBL24920727 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	NPC1	O15118	4/20	0.34

▸	RAB9A	P51151	4/20	0.34

▸	SMN1; SMN2	Q16637	4/20	0.34

▸	GAA	P10253	1/20	0.34

▸	CASP3	P42574	1/20	0.33

▸	SENP8	Q96LD8	1/20	0.33

▸	SENP7	Q9BQF6	1/20	0.33

▸	SENP6	Q9GZR1	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	TP53	P04637	1/20	0.30

▸	TSHR	P16473	1/20	0.30

▸	HSD17B10	Q99714	1/20	0.30

▸	MAPT	P10636	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24920854	0.90	ALOX5AP (0.34)	NPC1RAB9ASMN1; SMN2GAACASP3
SCHEMBL24920745	0.86	NPC1 (0.35)	NPC1RAB9ASMN1; SMN2GAACASP3
SCHEMBL24920723	0.84	NPC1 (0.35)	NPC1RAB9ASMN1; SMN2GAACASP3
SCHEMBL24920751	0.83	RAB9A (0.47)	NPC1RAB9ASMN1; SMN2GAACASP3
SCHEMBL24921666	0.81	NPC1 (0.36)	NPC1RAB9ASMN1; SMN2GAACASP3
SCHEMBL24920725	0.81	NPC1 (0.33)	NPC1RAB9ASMN1; SMN2GAACASP3
SCHEMBL24920730	0.81	NPC1 (0.35)	NPC1RAB9ASMN1; SMN2GAACASP3
SCHEMBL24920749	0.80	NPC1 (0.36)	NPC1RAB9ASMN1; SMN2GAACASP3
SCHEMBL24920736	0.80	NPC1 (0.34)	NPC1RAB9ASMN1; SMN2GAACASP3
SCHEMBL24920743	0.80	NPC1 (0.36)	NPC1RAB9ASMN1; SMN2GAACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023006097-A1	BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER	海创药业股份有限公司	2023-02-02	—	—	WO	disclosed