Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 10/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031860 | 0.78 | HPGDS (0.38) | PIM1PIM2NPC1CYP1A2CYP3A4 | |
| SCHEMBL24921789 | 0.77 | NPC1 (0.38) | ALDH1A1HPGDMAPK1NOTUMMAPT | |
| SCHEMBL24921240 | 0.74 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPK1NOTUMMAPT | |
| SCHEMBL25986827 | 0.74 | NOTUM (0.39) | ALDH1A1HPGDMAPK1NOTUMMAPT | |
| SCHEMBL25693366 | 0.74 | NOTUM (0.46) | ALDH1A1HPGDMAPK1NOTUMMAPT | |
| SCHEMBL25986910 | 0.74 | NOTUM (0.39) | ALDH1A1HPGDMAPK1NOTUMMAPT | |
| SCHEMBL24920778 | 0.74 | PIM1 (0.39) | PIM1PIM2NPC1RAB9ACYP1A2 | |
| SCHEMBL24921992 | 0.73 | MAPT (0.42) | ALDH1A1HPGDMAPK1NOTUMMAPT | |
| SCHEMBL5426257 | 0.73 | NOTUM (0.39) | ALDH1A1NOTUMMAPTPIM1PIM2 | |
| SCHEMBL24920803 | 0.72 | S1PR1 (0.35) | HPGDPIM1PIM2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |