Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.37 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.37 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920806 | 0.77 | GUCY1B2 (0.36) | MAPTHSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL24920793 | 0.76 | GUCY1B2 (0.40) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1L3MBTL1 | |
| SCHEMBL24922534 | 0.76 | PIK3CA (0.47) | MAPTHSD17B10KDM4EGAANPSR1 | |
| SCHEMBL24921481 | 0.75 | MAPT (0.46) | MAPTHSD17B10KDM4EGAANPSR1 | |
| SCHEMBL24920782 | 0.74 | PIM1 (0.36) | NPC1RAB9AGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL24920776 | 0.74 | L3MBTL1 (0.36) | MAPTHSD17B10KDM4EGAANPSR1 | |
| SCHEMBL24920791 | 0.72 | GUCY1B2 (0.35) | HSD17B10KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL24920882 | 0.72 | GUCY1B2 (0.42) | HSD17B10KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL16583245 | 0.71 | MAPT (0.47) | MAPTHSD17B10KDM4EGAANPSR1 | |
| SCHEMBL24921483 | 0.71 | L3MBTL1 (0.39) | MAPTHSD17B10KDM4EGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |