Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920818 | 0.77 | CYP1A2 (0.33) | HSD17B10HDAC1HDAC6HDAC5ALDH1A1 | |
| SCHEMBL24920831 | 0.76 | LRRK2 (0.36) | HDAC1HDAC6HDAC5AOC3LMNA | |
| SCHEMBL24921566 | 0.76 | MAPT (0.40) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL24921484 | 0.76 | L3MBTL1 (0.49) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL24920841 | 0.74 | MAPT (0.42) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL24920807 | 0.73 | LRRK2 (0.36) | HSD17B10ALDH1A1NPC1RAB9AAOC3 | |
| SCHEMBL24921982 | 0.72 | MAPT (0.40) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL24921462 | 0.71 | L3MBTL1 (0.40) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL24920816 | 0.71 | PDE10A (0.31) | HSD17B10ALDH1A1 | |
| SCHEMBL24920896 | 0.71 | CYP1A2 (0.31) | HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |