Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 4/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12245330 | 0.83 | RAB9A (0.50) | CYP3A4HPGDTSHRIGF1RSRC | |
| SCHEMBL2898728 | 0.78 | MEN1 (0.54) | ESR1ESR2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL4450783 | 0.76 | ESR1 (0.73) | ESR1ESR2CYP3A4HPGDAR | |
| SCHEMBL10865719 | 0.76 | ESR1 (0.73) | ESR1ESR2CYP3A4HPGDAR | |
| SCHEMBL4797887 | 0.73 | IGF1R (0.43) | HPGDIGF1RSRCALDH1A1MEN1 | |
| SCHEMBL2330756 | 0.73 | TEAD4 (0.47) | CYP3A4HPGDTSHRIGF1RSRC | |
| SCHEMBL12677967 | 0.73 | HTT (0.50) | HPGDTSHRHSD17B10IGF1RSRC | |
| SCHEMBL2904931 | 0.73 | ESR2 (0.48) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL24920856 | 0.73 | PIK3CD (0.41) | IGF1RSRCKMT2AKLKB1 | |
| SCHEMBL23292685 | 0.72 | IGF1R (0.50) | CYP3A4HPGDIGF1RSRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |