Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158354 | 1.00 | ALDH1A1 (0.50) | ALDH1A1PAOXUSP2HPGDMEN1 | |
| SCHEMBL20234238 | 1.00 | ALDH1A1 (0.50) | ALDH1A1PAOXUSP2HPGDMEN1 | |
| SCHEMBL20231214 | 1.00 | ALDH1A1 (0.50) | ALDH1A1PAOXUSP2HPGDMEN1 | |
| SCHEMBL10305196 | 0.98 | ALDH1A1 (0.51) | ALDH1A1PAOXUSP2HPGDMEN1 | |
| SCHEMBL24920416 | 0.94 | ALDH1A1 (0.46) | ALDH1A1PAOXUSP2HPGDMEN1 | |
| SCHEMBL11570576 | 0.93 | HRH3 (0.46) | ALDH1A1PAOXUSP2HPGDHRH3 | |
| SCHEMBL11569007 | 0.93 | HRH3 (0.46) | ALDH1A1PAOXUSP2HPGDHRH3 | |
| SCHEMBL10927336 | 0.93 | HRH3 (0.46) | ALDH1A1PAOXUSP2HPGDHRH3 | |
| SCHEMBL11573327 | 0.93 | HRH3 (0.46) | ALDH1A1PAOXUSP2HPGDHRH3 | |
| SCHEMBL27365597 | 0.92 | ALDH1A1 (0.45) | ALDH1A1PAOXUSP2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |