Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564720 | 0.92 | HRH3 (0.46) | ALDH1A1USP2HPGDHRH3PAOX | |
| SCHEMBL24920949 | 0.92 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDHRH3PAOX | |
| SCHEMBL20234238 | 0.92 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDHRH3PAOX | |
| SCHEMBL23158354 | 0.92 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDHRH3PAOX | |
| SCHEMBL20231214 | 0.92 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDHRH3PAOX | |
| SCHEMBL10305196 | 0.90 | ALDH1A1 (0.51) | ALDH1A1USP2HPGDHRH3PAOX | |
| SCHEMBL24920416 | 0.87 | ALDH1A1 (0.46) | ALDH1A1USP2HPGDPAOXMEN1 | |
| SCHEMBL13849154 | 0.86 | HRH3 (0.61) | ALDH1A1HRH3MEN1KMT2ACYP1A2 | |
| SCHEMBL11570576 | 0.86 | HRH3 (0.46) | ALDH1A1USP2HPGDHRH3PAOX | |
| SCHEMBL10927336 | 0.86 | HRH3 (0.46) | ALDH1A1USP2HPGDHRH3PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054604-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |