SCHEMBL24921985

SCHEMBL24921985

COc1ncc(-c2ncon2)nn1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.33
KMO O15229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24921552 0.77 FTO (0.37) KMO
SCHEMBL24921969 0.74 KMO (0.39) CNR2KMO
SCHEMBL24921988 0.74 CNR2 (0.36) CNR2KMO
SCHEMBL24921982 0.73 MAPT (0.40)
SCHEMBL24920774 0.71 PDPK1 (0.39) KMO
SCHEMBL24921978 0.70
SCHEMBL24921565 0.70 PDE10A (0.43) CNR2KMO
SCHEMBL24920838 0.70 CCR1 (0.34) CNR2KMO
SCHEMBL24921973 0.69 MAPT (0.42)
SCHEMBL6057257 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006097-A1 BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER 海创药业股份有限公司 2023-02-02 WO disclosed