Tenidap

Tenidap

SCHEMBL24922

NC(=O)N1C(=O)/C(=C(\O)c2cccs2)c2cc(Cl)ccc21

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
HTT P42858 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CNR2 P34972 1/20 0.40
KDM4E B2RXH2 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
LMNA P02545 2/20 0.39
APOBEC3A P31941 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
OPRM1 P35372 3/20 0.38
OPRD1 P41143 3/20 0.38
OPRK1 P41145 3/20 0.38
CCKBR P32239 1/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tenidap SCHEMBL3751878 1.00 MEN1 (0.42) MEN1KMT2AHTTCYP1A2CYP2C9
Tenidap SCHEMBL3751880 1.00 MEN1 (0.42) MEN1KMT2AHTTCYP1A2CYP2C9
Tenidap SCHEMBL30597938 0.86 KMT2A (0.41) MEN1KMT2AHTTCYP1A2CYP2C9
Tenidap SCHEMBL43098 0.86 KMT2A (0.41) MEN1KMT2AHTTCYP1A2CYP2C9
Tenidap SCHEMBL9216494 0.85 ALDH1A1 (0.33) HTTNPSR1ALDH1A1HSP90AA1
SCHEMBL9215467 0.84 ALDH1A1 (0.36) MEN1KMT2AHTTCYP1A2CYP2C9
SCHEMBL8816115 0.84 CHEK1 (0.41) KMT2AKDM4EALDH1A1RXFP1
SCHEMBL8816112 0.84 CHEK1 (0.41) KMT2AKDM4EALDH1A1RXFP1
SCHEMBL3676246 0.83 ALDH1A1 (0.33) HTTNPSR1ALDH1A1HSP90AA1
Ilonidap SCHEMBL42518 0.83 ALDH1A1 (0.35) MEN1KMT2AHTTCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17044 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000741-A1 METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE ACERAGEN INC (US) 2026-01-01 US claimed
US-12297294-B2 Cortistatin analogues for the treatment of inflammatory and/or immune diseases BCN PEPTIDES, S.A. (ES) 2025-05-13 US claimed
US-20250041208-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2025-02-06 US claimed
CN-112770764-B Methods of treating infections using bacteria 因达普特斯治疗有限公司 2024-12-03 CN claimed
EP-4444277-A1 NEW INJECTABLE COMBINATION FORMULATION Nanexa AB (SE) 2024-10-16 EP claimed
CN-118647367-A Novel injectable combination formulations 南爱克萨股份公司 2024-09-13 CN claimed
CN-118512401-A Lipid vesicle compositions with permeation enhancers 迪迪艾斯研究公司 2024-08-20 CN claimed
CN-115175667-B Lipid vesicle compositions with permeation enhancers 迪迪艾斯研究公司 2024-06-04 CN claimed
EP-4335413-A2 PROSTHETIC TISSUE VALVES Cormatrix Cardiovascular, Inc. (US) 2024-03-13 EP claimed
EP-3856213-B1 METHODS OF TREATMENT OF INFECTIONS USING BACTERIA INDAPTUS THERAPEUTICS INC (US) 2024-03-06 EP claimed
US-5308839-A Nonsteroid antiinflammatory agents THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1994-05-03 US claimed
EP-0586020-A1 Tetracyclines alone or in combination with NSAID for treating tissue destruction THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1994-03-09 EP claimed
WO-1994000130-A1 COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1994-01-06 WO claimed
WO-1993013758-A1 PREPARATION OF TABLETS OF INCREASED STRENGTH PFIZER INC. (US) 1993-07-22 WO claimed
EP-0498588-A1 Use of tenidap to reduce total serum cholesterol, LDL cholesterol and triglycerides PFIZER INC. (US) 1992-08-12 EP claimed
US-5122534-A USE OF TENIDAP TO REDUCE TOTAL SERUM CHOLESTEROL, LDL CHOLESTEROL AND TRIGLYCERIDES PFIZER INC. (US) 1992-06-16 US claimed
EP-0448261-A2 Tenidap as an inhibitor of the release of elastase by neutrophils PFIZER INC. (US) 1991-09-25 EP claimed
EP-0448253-A2 Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase PFIZER INC. (US) 1991-09-25 EP claimed
US-5008283-A Antiinflammatory agents; vision, skin and bone disorders PFIZER INC. (US) 1991-04-16 US claimed
US-5006547-A Tenidap as an inhibitor of the release of elastase by neutrophils PFIZER INC. (US) 1991-04-09 US claimed