Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30399915 | 0.81 | LTA4H (0.56) | LTA4HALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25986532 | 0.81 | LTA4H (0.56) | LTA4HALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30212233 | 0.79 | CHRNB2 (0.39) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL24921453 | 0.79 | CHRNB2 (0.39) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL29994942 | 0.77 | — | — | |
| SCHEMBL502881 | 0.77 | — | — | |
| SCHEMBL24921857 | 0.77 | CACNA1I (0.46) | LTA4HALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL24922130 | 0.77 | HRH3 (0.41) | LTA4HALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL29226462 | 0.76 | AOC3 (0.40) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL29226458 | 0.76 | AOC3 (0.40) | ALDH1A1MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |