⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22433124 | 0.89 | — | — | |
| SCHEMBL22433442 | 0.88 | NLRP3 (0.47) | — | |
| SCHEMBL22433082 | 0.88 | NLRP3 (0.49) | — | |
| SCHEMBL20634281 | 0.87 | EPHX2 (0.43) | — | |
| SCHEMBL20634275 | 0.87 | EPHX2 (0.47) | — | |
| SCHEMBL22433573 | 0.87 | — | — | |
| SCHEMBL22433086 | 0.87 | NLRP3 (0.48) | — | |
| SCHEMBL22433122 | 0.86 | NLRP3 (0.47) | — | |
| SCHEMBL22433439 | 0.85 | NLRP3 (0.51) | — | |
| SCHEMBL22433383 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230037255-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LTD (IE) | 2023-02-02 | — | — | US | disclosed |