SCHEMBL20634281

SCHEMBL20634281

CCC(=O)N1CCC(S(=O)(=O)NC(=O)Nc2c(C(C)C)cc(F)cc2C(C)C)CC1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 8/20 0.43
▸ NPY5R Q15761 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20634275 0.90 EPHX2 (0.47) EPHX2
SCHEMBL22433127 0.89 HSD17B10 (0.36) —
SCHEMBL22433123 0.88 GSTO1 (0.37) EPHX2
SCHEMBL20634276 0.88 ALDH1A1 (0.40) —
SCHEMBL22433572 0.87 RECQL (0.41) —
SCHEMBL24922408 0.87 — —
SCHEMBL22433085 0.87 EPHX2 (0.39) EPHX2NPY5R
SCHEMBL22433120 0.86 PKM (0.37) EPHX2
SCHEMBL20636155 0.86 GSTO1 (0.39) —
SCHEMBL20634271 0.85 TP53 (0.37) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230037255-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LTD (IE) 2023-02-02 — — US disclosed
WO-2019008025-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LIMITED (IE) 2019-01-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230037255-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS NLRP3, NOD1, NLRP1 EPHX2 2904/4885NPY5R 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback